Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CobI_2precorrin-6A synthase deacetylating. (254 aa)    
Predicted Functional Partners:
CobK
Cobalt-precorrin-6x reductase.
 
 
 0.997
CobM
Precorrin-4 c11-methyltransferase cobM; Belongs to the precorrin methyltransferase family.
 
 
 0.991
CobL
Precorrin-6y methyltransferase cobL.
 
  
 0.959
CobH
precorrin-8X methylmutase.
 
  
 0.922
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.801
CobI_1
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family.
 
  
0.801
CobN
Cobalamin biosynthesis protein cobN.
 
  
 0.702
BtuR
cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
   
 0.701
RMCT_4354
Cobalamin biosynthesis protein cobG.
 
  
 0.695
RMCT_1690
Integral membrane protein.
       0.565
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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