Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RMCT_18304-amino-4-deoxychorismate lyase. (284 aa)    
Predicted Functional Partners:
PabB
Para-aminobenzoate synthase component I pabD.
  
 
 0.966
FolP2
Dihydropteroate synthase 2 folP2.
  
 
 0.930
FolP1
Dihydropteroate synthase 1 folp.
  
 
 0.930
TrpG
Para-aminobenzoate synthase component II.
  
 
 0.927
RMCT_3617
Putative uncharacterized protein.
     
  0.900
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.707
YngG_2
hydroxymethylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.698
YgfZ
Folate-binding protein YgfZ; Belongs to the GcvT family.
     
 0.661
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.635
BphI
4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
 
 0.635
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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