| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdhC2 | AldA_5 | RMCT_3597 | RMCT_1878 | NADP-dependent alcohol dehydrogenase C. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.935 |
| AdhC2 | BphJ | RMCT_3597 | RMCT_1944 | NADP-dependent alcohol dehydrogenase C. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.906 |
| AldA_5 | AdhC2 | RMCT_1878 | RMCT_3597 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | NADP-dependent alcohol dehydrogenase C. | 0.935 |
| AldA_5 | BphJ | RMCT_1878 | RMCT_1944 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.910 |
| AldA_5 | GadA | RMCT_1878 | RMCT_0558 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | 0.928 |
| AldA_5 | GarR_3 | RMCT_1878 | RMCT_1876 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Dehydrogenase/reductase. | 0.937 |
| AldA_5 | GdhA | RMCT_1878 | RMCT_1548 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.926 |
| AldA_5 | MmsA | RMCT_1878 | RMCT_0519 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Methylmalonate-semialdehyde dehydrogenase. | 0.917 |
| AldA_5 | RMCT_1875 | RMCT_1878 | RMCT_1875 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Gamma-carboxymuconolactone decarboxylase subunit like protein. | 0.917 |
| AldA_5 | RMCT_4229 | RMCT_1878 | RMCT_4229 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Lactate 2-monooxygenase. | 0.915 |
| AldA_5 | acsA | RMCT_1878 | RMCT_0114 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.931 |
| AldA_5 | panD | RMCT_1878 | RMCT_3318 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.913 |
| BphJ | AdhC2 | RMCT_1944 | RMCT_3597 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | NADP-dependent alcohol dehydrogenase C. | 0.906 |
| BphJ | AldA_5 | RMCT_1944 | RMCT_1878 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| BphJ | MmsA | RMCT_1944 | RMCT_0519 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Methylmalonate-semialdehyde dehydrogenase. | 0.821 |
| BphJ | acsA | RMCT_1944 | RMCT_0114 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.909 |
| GadA | AldA_5 | RMCT_0558 | RMCT_1878 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.928 |
| GadA | GdhA | RMCT_0558 | RMCT_1548 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.915 |
| GadA | panD | RMCT_0558 | RMCT_3318 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.906 |
| GarR_3 | AldA_5 | RMCT_1876 | RMCT_1878 | Dehydrogenase/reductase. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.937 |