| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BphI | BphJ | RMCT_1943 | RMCT_1944 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.999 |
| BphI | C2-hpah | RMCT_1943 | RMCT_3184 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | acyl-CoA dehydrogenase type 2. | 0.716 |
| BphI | HsaD_1 | RMCT_1943 | RMCT_0488 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Alpha/beta hydrolase. | 0.709 |
| BphI | HsaD_3 | RMCT_1943 | RMCT_2899 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphD. | 0.765 |
| BphI | KsdD | RMCT_1943 | RMCT_1946 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 3-ketosteroid-delta-1-dehydrogenase. | 0.748 |
| BphI | MhpD | RMCT_1943 | RMCT_1945 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 2-keto-4-pentenoate hydratase. | 0.998 |
| BphI | RMCT_1947 | RMCT_1943 | RMCT_1947 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Dehydrogenase. | 0.829 |
| BphI | leuB | RMCT_1943 | RMCT_3538 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.766 |
| BphI | leuC | RMCT_1943 | RMCT_3533 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.721 |
| BphI | leuD | RMCT_1943 | RMCT_3532 | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.712 |
| BphJ | BphI | RMCT_1944 | RMCT_1943 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.999 |
| BphJ | HsaD_1 | RMCT_1944 | RMCT_0488 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Alpha/beta hydrolase. | 0.561 |
| BphJ | HsaD_3 | RMCT_1944 | RMCT_2899 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphD. | 0.636 |
| BphJ | KsdD | RMCT_1944 | RMCT_1946 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 3-ketosteroid-delta-1-dehydrogenase. | 0.709 |
| BphJ | MhpD | RMCT_1944 | RMCT_1945 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-keto-4-pentenoate hydratase. | 0.991 |
| BphJ | RMCT_1947 | RMCT_1944 | RMCT_1947 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Dehydrogenase. | 0.486 |
| C2-hpah | BphI | RMCT_3184 | RMCT_1943 | acyl-CoA dehydrogenase type 2. | 4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.716 |
| C2-hpah | HsaD_1 | RMCT_3184 | RMCT_0488 | acyl-CoA dehydrogenase type 2. | Alpha/beta hydrolase. | 0.759 |
| C2-hpah | HsaD_3 | RMCT_3184 | RMCT_2899 | acyl-CoA dehydrogenase type 2. | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphD. | 0.794 |
| C2-hpah | KsdD | RMCT_3184 | RMCT_1946 | acyl-CoA dehydrogenase type 2. | 3-ketosteroid-delta-1-dehydrogenase. | 0.554 |
