STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fgd1_45,10-methylenetetrahydromethanopterin reductase. (318 aa)    
Predicted Functional Partners:
RMCT_4121
F420-dependent oxidoreductase, MSMEG_4879 family.
  
  
  0.934
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.906
RMCT_4399
Hypothetical protein.
 
   
 0.584
CofD
LPPG:FO 2-phospho-L-lactate transferase.
 
   
 0.559
RMCT_1627
Putative aminoglycoside phosphotransferase.
 
     0.555
RMCT_3423
Luciferase-like protein.
  
     0.536
DrgA_1
Nitroreductase.
 
  
 0.532
Fgd_3
Oxidoreductase.
  
     0.531
KshA_6
Iron-sulfur cluster-binding protein, Rieske family protein.
       0.531
RMCT_2287
F420-0--gamma-glutamyl ligase.
 
  
 0.531
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.