| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Efe | MetQ | RMCT_2790 | RMCT_1987 | 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family. | NLPA lipoprotein. | 0.504 |
| FprA_2 | MdeA_1 | RMCT_3056 | RMCT_0623 | NADPH:adrenodoxin oxidoreductase fprA. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.819 |
| FprA_2 | MetQ | RMCT_3056 | RMCT_1987 | NADPH:adrenodoxin oxidoreductase fprA. | NLPA lipoprotein. | 0.545 |
| MdeA_1 | FprA_2 | RMCT_0623 | RMCT_3056 | O-acetylhomoserine aminocarboxypropyltransferase. | NADPH:adrenodoxin oxidoreductase fprA. | 0.819 |
| MdeA_1 | MetH | RMCT_0623 | RMCT_3940 | O-acetylhomoserine aminocarboxypropyltransferase. | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
| MdeA_1 | MetN_2 | RMCT_0623 | RMCT_1985 | O-acetylhomoserine aminocarboxypropyltransferase. | ABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | 0.422 |
| MdeA_1 | MetQ | RMCT_0623 | RMCT_1987 | O-acetylhomoserine aminocarboxypropyltransferase. | NLPA lipoprotein. | 0.759 |
| MdeA_1 | cysC | RMCT_0623 | RMCT_1372 | O-acetylhomoserine aminocarboxypropyltransferase. | Bifunctional sulfate adenyltransferase/adenylylsulfate kinase cysN/cysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.754 |
| MdeA_1 | metK | RMCT_0623 | RMCT_3652 | O-acetylhomoserine aminocarboxypropyltransferase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.516 |
| MetH | MdeA_1 | RMCT_3940 | RMCT_0623 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.976 |
| MetH | MetI | RMCT_3940 | RMCT_1986 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Binding-protein-dependent transport system inner membrane protein. | 0.400 |
| MetH | MetN_2 | RMCT_3940 | RMCT_1985 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | 0.497 |
| MetH | MetQ | RMCT_3940 | RMCT_1987 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NLPA lipoprotein. | 0.534 |
| MetH | RMCT_4090 | RMCT_3940 | RMCT_4090 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.978 |
| MetH | cysC | RMCT_3940 | RMCT_1372 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Bifunctional sulfate adenyltransferase/adenylylsulfate kinase cysN/cysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.675 |
| MetH | metK | RMCT_3940 | RMCT_3652 | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.969 |
| MetI | MetH | RMCT_1986 | RMCT_3940 | Binding-protein-dependent transport system inner membrane protein. | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.400 |
| MetI | MetN_2 | RMCT_1986 | RMCT_1985 | Binding-protein-dependent transport system inner membrane protein. | ABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | 0.999 |
| MetI | MetQ | RMCT_1986 | RMCT_1987 | Binding-protein-dependent transport system inner membrane protein. | NLPA lipoprotein. | 0.999 |
| MetI | MoxC | RMCT_1986 | RMCT_1984 | Binding-protein-dependent transport system inner membrane protein. | Xenobiotic compound monooxygenase, DszA family. | 0.850 |