Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
IrtADrug ABC transporter ATP-binding protein. (908 aa)    
Predicted Functional Partners:
IrtB
Drug ABC transporter ATP-binding protein.
 
 
0.999
MbtB_2
Phenyloxazoline synthase mbtB.
 
  
 0.944
DhbE_1
Bifunctional enzyme mbtA: salicyl-AMP ligase + salicyl-S-arcp synthetase.
 
  
 0.864
PpsA_7
Polyketide synthase pks13.
 
 
 0.838
LgrD_2
Linear gramicidin synthetase subunit D.
  
 
 0.802
RMCT_4707
Linear gramicidin synthetase subunit D.
  
 
 0.802
RMCT_0772
lysine-N-oxygenase mbtG.
 
  
 0.798
PpsA_2
Beta-ketoacyl synthase.
  
 0.773
Pks2
Polyketide synthase pks5.
 
 0.749
EccA1_2
ATPase central domain-containing protein.
 
 
 0.741
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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