Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RMCT_2072TetR family transcriptional regulator. (404 aa)    
Predicted Functional Partners:
LutR
GntR family transcriptional regulator.
 
  
 0.742
cobB-2
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.701
RMCT_2435
TetR family transcriptional regulator.
   
    0.692
MsrR_3
Transcriptional regulator.
   
    0.653
RMCT_3136
Transcriptional regulatory protein.
  
    0.646
EthR_1
Transcriptional regulator.
   
  
 0.597
GerE
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
  
 0.597
RMCT_0513
Transcriptional regulator.
  
  
 0.582
TetC
TetR family transcriptional regulator.
   
    0.562
cobB
NAD-dependent protein deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
  
 0.542
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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