Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HsdA_53-alpha-hydroxysteroid dehydrogenase. (258 aa)    
Predicted Functional Partners:
XylF
Alpha/beta hydrolase fold protein.
 
  0.897
RMCT_2233
Cyclase.
 
  
 0.886
HsaD_2
Alpha/beta hydrolase fold protein.
 
 0.858
Azo1
NADPH-dependent FMN reductase.
     
 0.839
FabG3_1
Dehydrogenase.
 
    
0.820
LimB_4
Luciferase family protein.
 
   
 0.802
mhpB
2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
   
 0.799
KstD_4
Succinate dehydrogenase/fumarate reductase flavoprotein subunit.
  
  
 0.749
BdhA_2
Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.737
CpnA_2
Short-chain dehydrogenase of unknown substrate specificity.
 
 
 
 0.721
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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