Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XylFAlpha/beta hydrolase fold protein. (283 aa)    
Predicted Functional Partners:
HsdA_5
3-alpha-hydroxysteroid dehydrogenase.
 
  0.897
FabG3_1
Dehydrogenase.
  
  0.870
RMCT_2233
Cyclase.
     
 0.863
Azo1
NADPH-dependent FMN reductase.
       0.855
mhpB
2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.814
HsaD_2
Alpha/beta hydrolase fold protein.
 
    
0.782
LimB_4
Luciferase family protein.
  
  
 0.750
mhpA
2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
 
 0.725
KstD_4
Succinate dehydrogenase/fumarate reductase flavoprotein subunit.
     
 0.712
CatD_1
Alpha/beta hydrolase fold protein.
  
     0.647
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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