Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RMCT_2273Hypothetical protein. (93 aa)    
Predicted Functional Partners:
AccD5_1
propionyl-CoA carboxylase beta subunit 5 accD5.
  
 0.999
AccC_2
Bifunctional protein acetyl-/propionyl-coenzyme A carboxylase alpha subunit accA3: biotin carboxylase + biotin carboxyl carrier protein.
   
 0.995
AccD5_2
propionyl-CoA carboxylase beta subunit 4 accD4.
  
 0.990
KasA_2
Fatty acid synthase.
   
 
 0.962
AccA1_1
Urea amidolyase.
   
 
 0.953
AccD6
propionyl-CoA carboxylase beta subunit 6 accD6.
  
 0.944
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
     
 0.905
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
  0.900
MmsA
Methylmalonate-semialdehyde dehydrogenase.
     
  0.900
AcsA_3
acyl-CoA synthetase/AMP-acid ligase.
     
  0.900
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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