STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AccD5_1propionyl-CoA carboxylase beta subunit 5 accD5. (548 aa)    
Predicted Functional Partners:
AccC_2
Bifunctional protein acetyl-/propionyl-coenzyme A carboxylase alpha subunit accA3: biotin carboxylase + biotin carboxyl carrier protein.
 
 0.998
RMCT_2273
Hypothetical protein.
  
 
 0.997
AccA1_2
Acetyl-/propionyl-coenzyme A carboxylase subunit alpha.
 
 0.988
RMCT_2179
methylmalonyl-CoA epimerase.
 
 
 0.964
BirA
biotin--acetyl-CoA-carboxylase ligase.
 
 
 0.944
RMCT_3765
acyl-CoA oxidase.
  
 
 0.933
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.932
AcsA_3
acyl-CoA synthetase/AMP-acid ligase.
  
 0.931
MmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.918
AccD6
propionyl-CoA carboxylase beta subunit 6 accD6.
  
  
0.914
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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