Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ManAMannose-6-phosphate isomerase manA. (408 aa)    
Predicted Functional Partners:
PmmA
Phosphomannomutase/phosphoglucomutase.
  
 
 0.994
glmS
Glucosamine-fructose-6-phosphate aminotransferase glmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.947
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.939
pgi-2
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.939
RMCT_3438
Phosphomannomutase.
  
 
 0.923
RMCT_2293
TobH protein.
  
    0.921
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.916
PfkB_1
6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.914
IolC
Sugar kinase, ribokinase.
    
 0.911
GlpX
Fructose 1,6-bisphosphatase II.
     
 0.905
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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