aroA protein (Mycolicibacterium thermoresistibile)

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aroA

3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (420 aa)

Predicted Functional Partners:

aroC

0.992

aroE

0.991

aroB

0.986

aroK

0.985

TyrC

0.939

RsgA

0.930

cmk

0.919

YedK

0.826

RMCT_1677

0.822

pheT

0.737

Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RMCT_1677	TyrC	RMCT_1677	RMCT_0032	Chorismate mutase.	Prephenate dehydrogenase.	0.962
RMCT_1677	aroA	RMCT_1677	RMCT_2323	Chorismate mutase.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.822
RMCT_1677	aroB	RMCT_1677	RMCT_3677	Chorismate mutase.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.456
RMCT_1677	aroC	RMCT_1677	RMCT_3679	Chorismate mutase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.975
RMCT_1677	aroE	RMCT_1677	RMCT_3683	Chorismate mutase.	Shikimate 5-dehydrogenase.	0.594
RMCT_1677	aroK	RMCT_1677	RMCT_3678	Chorismate mutase.	Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.604
RMCT_1677	pheT	RMCT_1677	RMCT_4494	Chorismate mutase.	phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.636
RsgA	YedK	RMCT_2322	RMCT_2324	Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Bacteriophage protein; Belongs to the SOS response-associated peptidase family.	0.826
RsgA	aroA	RMCT_2322	RMCT_2323	Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.930
TyrC	RMCT_1677	RMCT_0032	RMCT_1677	Prephenate dehydrogenase.	Chorismate mutase.	0.962
TyrC	aroA	RMCT_0032	RMCT_2323	Prephenate dehydrogenase.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.939
TyrC	aroB	RMCT_0032	RMCT_3677	Prephenate dehydrogenase.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.856
TyrC	aroC	RMCT_0032	RMCT_3679	Prephenate dehydrogenase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.882
TyrC	aroE	RMCT_0032	RMCT_3683	Prephenate dehydrogenase.	Shikimate 5-dehydrogenase.	0.451
TyrC	aroK	RMCT_0032	RMCT_3678	Prephenate dehydrogenase.	Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.757
TyrC	cmk	RMCT_0032	RMCT_2133	Prephenate dehydrogenase.	Cytidylate kinase.	0.772
YedK	RsgA	RMCT_2324	RMCT_2322	Bacteriophage protein; Belongs to the SOS response-associated peptidase family.	Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.826
YedK	aroA	RMCT_2324	RMCT_2323	Bacteriophage protein; Belongs to the SOS response-associated peptidase family.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.826
aroA	RMCT_1677	RMCT_2323	RMCT_1677	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Chorismate mutase.	0.822
aroA	RsgA	RMCT_2323	RMCT_2322	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.930

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