Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RMCT_2330Anti-sigma factor. (105 aa)    
Predicted Functional Partners:
RpoE_2
Alternative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.937
CnrH
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.732
whiB-6
Transcriptional regulatory protein whib-like whiB7; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.724
RMCT_2636
Protein of unknown function.
 
     0.662
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
 
 0.639
RMCT_2327
Short-chain dehydrogenase.
     
 0.639
whiB-3
WhiB family regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
 
 0.628
RMCT_1818
Protein of unknown function.
 
     0.624
UbiE_2
Type 11 methyltransferase.
       0.589
SigE
ECF subfamily RNA polymerase sigma-24 subunit; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.588
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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