Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GarLhpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (245 aa)    
Predicted Functional Partners:
MhpD
2-keto-4-pentenoate hydratase.
  
 0.816
RMCT_2399
Taurine catabolism dioxygenase TauD, TfdA family.
 
     0.789
GhrB
Phosphoglycerate dehydrogenase-like oxidoreductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
     0.731
CaiD_5
enoyl-CoA hydratase/isomerase family protein.
       0.663
mhpB
2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.579
RMCT_2396
Putative uncharacterized protein.
       0.556
RMCT_2397
Thiolase.
       0.553
RMCT_2402
Putative uncharacterized protein.
       0.548
GarR_2
6-phosphogluconate dehydrogenase.
 
  
 0.473
GarR_1
6-phosphogluconate dehydrogenase.
 
  
 0.472
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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