Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CcdACytochrome c biogenesis protein, transmembrane region. (273 aa)    
Predicted Functional Partners:
CcsB
Cytochrome c assembly protein.
 
  
 0.993
ResA_1
Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.
 
  
 0.991
RMCT_2598
Transmembrane protein.
 
  
 0.983
hemL
Glutamate-1-semialdehyde aminotransferase.
  
  
 0.963
RMCT_2601
Fructose-2,6-bisphosphatase.
  
    0.922
hemE
Uroporphyrinogen decarboxylase hemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.705
ResA_2
Thiol-disulfide isomerase-like thioredoxin.
 
  
 0.700
RMCT_2603
Protein of unknown function.
       0.665
Mpt53
Soluble secreted antigen mpt53 precursor.
  
  
 0.640
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.631
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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