Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MlcROK family protein. (442 aa)    
Predicted Functional Partners:
mshA
Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
     
 0.762
RMCT_2636
Protein of unknown function.
       0.747
Sdh_1
Short-chain type oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.729
Sir
Ferredoxin-dependent nitrite reductase nirA; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.501
RMCT_4008
Secreted protein.
 
   
 0.500
RMCT_3675
Transmembrane protein.
  
     0.479
RMCT_1387
Lipoprotein lprB.
 
     0.476
RMCT_1386
Lipoprotein lprC.
 
     0.467
RMCT_1816
Hypothetical protein.
  
     0.445
PrrB
Two component system sensor histidine kinase prrB.
 
   
 0.430
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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