Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LpdDihydrolipoamide dehydrogenase. (466 aa)    
Predicted Functional Partners:
Kgd
Alpha-ketoglutarate decarboxylase.
 
 0.999
AcoB
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit.
 
 0.998
DlaT
Dihydrolipoamide acetyltransferase.
 0.996
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.994
PdhB
Pyruvate dehydrogenase E1 component beta subunit pdhB.
 
 0.989
PdhA
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
 
 
 0.982
AceE_2
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.981
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.977
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.975
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.966
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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