STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LpdDihydrolipoamide dehydrogenase. (466 aa)    
Predicted Functional Partners:
AcoB
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit.
 
 0.999
Kgd
Alpha-ketoglutarate decarboxylase.
 
 0.999
DlaT
Dihydrolipoamide acetyltransferase.
 0.998
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.995
PdhB
Pyruvate dehydrogenase E1 component beta subunit pdhB.
 
 0.993
PdhA
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
 
 
 0.989
AceE_2
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.984
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.982
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.976
AceE_1
Pyruvate dehydrogenase E1 component.
  
 
 0.955
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.