Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KstR2_8Transcription regulator AmtR. (234 aa)    
Predicted Functional Partners:
RMCT_2794
Urea carboxylase-associated protein 2.
 
     0.834
SglT
Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
     
 0.796
AccA1_1
Urea amidolyase.
 
 
 
 0.795
RMCT_2793
Urea carboxylase-associated protein 1.
 
     0.794
GatA_2
Allophanate hydrolase.
 
   
 0.762
glnD
PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
     
 0.619
GlnB
Nitrogen regulatory protein P-II glnB; Belongs to the P(II) protein family.
     
 0.587
Efe
2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.
     
 0.575
RMCT_2787
Exported protein.
     
 0.461
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.443
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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