Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RMCT_2867TetR family transcriptional regulator. (244 aa)    
Predicted Functional Partners:
RMCT_2435
TetR family transcriptional regulator.
  
    0.685
EthR_1
Transcriptional regulator.
   
  
 0.655
MsrR_3
Transcriptional regulator.
   
    0.633
RMCT_3156
Transcriptional regulator.
  
  
 0.577
RMCT_3099
Transcriptional regulator.
   
  
 0.564
RMCT_3037
Response regulator.
  
  
 0.555
cobB
NAD-dependent protein deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
 
  
 0.550
LutR
GntR family transcriptional regulator.
  
  
 0.546
RMCT_2868
Putative uncharacterized protein.
       0.545
cobB-2
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.535
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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