Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EthR_2TetR family transcriptional regulator. (203 aa)    
Predicted Functional Partners:
YngG_1
hydroxymethylglutaryl-CoA lyase.
     
 0.875
RMCT_3045
Homogentisate 1,2-dioxygenase.
 
     0.870
RMCT_3044
Alpha/beta hydrolase fold protein.
 
     0.866
Frc_5
formyl-CoA transferase; Belongs to the CoA-transferase III family.
  
    0.806
RMCT_3039
Aminoglycoside phosphotransferase.
       0.779
RMCT_3040
acyl-CoA dehydrogenase.
       0.779
CysL
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
 
 0.729
RMCT_3037
Response regulator.
  
  
 0.728
IdeR_1
Transcriptional repressor sirR.
  
  
 0.721
cobB-2
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.720
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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