Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GmrGAF sensor-containing diguanylate cyclase/phosphodiesterase. (613 aa)    
Predicted Functional Partners:
AdrA
Diguanylate cyclase.
 
 
 0.993
RMCT_4559
Stage II sporulation protein E.
  
 
 0.993
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
 
 0.968
RMCT_3377
Putative uncharacterized protein.
  
  
 0.935
YeaP
Diguanylate cyclase.
 
 
 0.924
RMCT_3376
Putative uncharacterized protein.
 
     0.862
TetR_2
TetR family transcriptional regulator.
  
  
 0.795
Cph1
Two-component system sensor kinase.
  
  
 0.741
RMCT_0610
Integral membrane sensor signal transduction histidine kinase.
 
 
 0.718
DevS
GAF sensor signal transduction histidine kinase.
 
 0.708
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.