Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EthA_3Monooxygenase EthA. (493 aa)    
Predicted Functional Partners:
EthR_7
TetR family transcriptional regulator.
 
   
 0.893
PamO_2
Monooxygenase.
  
     0.699
RMCT_2820
Short-chain type dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.679
EphA
Epoxide hydrolase ephA.
  
 
 0.592
DesA3
linoleoyl-CoA desaturase.
 
   
 0.584
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.567
Tgs2_3
Putative diacylglycerol O-acyltransferase; Belongs to the long-chain O-acyltransferase family.
 
 
 0.558
BpoC_2
Lipase/esterase lipG.
 
 0.489
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.486
CzcD
Cation diffusion facilitator family transporter.
  
  
 0.465
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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