mutM protein (Mycolicibacterium thermoresistibile)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MutM_3	MutY	RMCT_1685	RMCT_3331	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	Adenine glycosylase mutY.	0.614
MutM_3	dnaQ-2	RMCT_1685	RMCT_3881	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	DNA polymerase III subunit epsilon.	0.701
MutM_3	mutM	RMCT_1685	RMCT_3505	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.930
MutM_3	polA	RMCT_1685	RMCT_4464	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.641
MutM_3	uvrC	RMCT_1685	RMCT_3635	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.495
MutY	MutM_3	RMCT_3331	RMCT_1685	Adenine glycosylase mutY.	formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.	0.614
MutY	dinB-3	RMCT_3331	RMCT_4386	Adenine glycosylase mutY.	DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	0.506
MutY	dnaQ-2	RMCT_3331	RMCT_3881	Adenine glycosylase mutY.	DNA polymerase III subunit epsilon.	0.471
MutY	mutM	RMCT_3331	RMCT_3505	Adenine glycosylase mutY.	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.711
MutY	polA	RMCT_3331	RMCT_4464	Adenine glycosylase mutY.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.652
MutY	uvrC	RMCT_3331	RMCT_3635	Adenine glycosylase mutY.	Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.460
RMCT_3507	RMCT_3508	RMCT_3507	RMCT_3508	Metal-binding protein.	Cell division initiation protein.	0.869
RMCT_3507	mutM	RMCT_3507	RMCT_3505	Metal-binding protein.	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.883
RMCT_3507	rnc	RMCT_3507	RMCT_3506	Metal-binding protein.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.962
RMCT_3508	RMCT_3507	RMCT_3508	RMCT_3507	Cell division initiation protein.	Metal-binding protein.	0.869
RMCT_3508	mutM	RMCT_3508	RMCT_3505	Cell division initiation protein.	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.630
RMCT_3508	polA	RMCT_3508	RMCT_4464	Cell division initiation protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.460
RMCT_3508	rnc	RMCT_3508	RMCT_3506	Cell division initiation protein.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.819
RecN	dinB-3	RMCT_2113	RMCT_4386	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	0.491
RecN	dnaQ-2	RMCT_2113	RMCT_3881	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	DNA polymerase III subunit epsilon.	0.478

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