Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IscSCysteine desulfurase iscS. (398 aa)    
Predicted Functional Partners:
NifU
Nitrogen fixation-like protein.
  
 0.994
MoeZ
Molybdopterin biosynthesis-like protein MoeZ.
   
 0.985
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase trmU; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.946
SseA_2
Thiosulfate sulfurtransferase sseB.
  
 0.937
RMCT_1817
Thiosulfate sulfurtransferase.
  
 0.937
SseA_1
Thiosulfate sulfurtransferase.
  
 0.937
RMCT_3863
Iron-sulfur cluster biosynthesis protein; Belongs to the HesB/IscA family.
 
 
 0.899
DnaK_4
Molecular chaperone-like protein.
 
 0.810
DnaK_2
Putative uncharacterized protein.
 
 0.795
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.792
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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