Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
FabRTetR family transcriptional regulator. (250 aa)    
Predicted Functional Partners:
nrdI
Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function.
  
    0.755
RMCT_3606
Geranylgeranyl reductase.
 
   
 0.621
NrdH
Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit.
  
    0.491
NrdE_2
Ribonucleoside-diphosphate reductase large subunit nrdZ; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
    0.486
NrdE_1
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
    0.486
RMCT_0740
Alanine rich transmembrane protein.
  
     0.477
RMCT_2840
Transcriptional regulator.
  
   
 0.452
RMCT_1666
Putative uncharacterized protein.
 
     0.448
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.443
RMCT_4125
Acyl dehydratase.
 
   
 0.437
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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