| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MazG | SurE | RMCT_1525 | RMCT_1179 | Nucleoside triphosphate pyrophosphohydrolase. | Survival protein SurE. | 0.910 |
| MazG | pyrF | RMCT_1525 | RMCT_3657 | Nucleoside triphosphate pyrophosphohydrolase. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.909 |
| MazG | pyrH | RMCT_1525 | RMCT_4235 | Nucleoside triphosphate pyrophosphohydrolase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.910 |
| MazG | pyrR | RMCT_1525 | RMCT_3663 | Nucleoside triphosphate pyrophosphohydrolase. | Pyrimidine operon regulatory protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.920 |
| MazG | upp | RMCT_1525 | RMCT_3437 | Nucleoside triphosphate pyrophosphohydrolase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.911 |
| RMCT_3660 | carA | RMCT_3660 | RMCT_3659 | Export or membrane protein. | Carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.960 |
| RMCT_3660 | carB | RMCT_3660 | RMCT_3658 | Export or membrane protein. | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.990 |
| RMCT_3660 | pyrB | RMCT_3660 | RMCT_3662 | Export or membrane protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.961 |
| RMCT_3660 | pyrC | RMCT_3660 | RMCT_3661 | Export or membrane protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.963 |
| RMCT_3660 | pyrF | RMCT_3660 | RMCT_3657 | Export or membrane protein. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.964 |
| RMCT_3660 | pyrR | RMCT_3660 | RMCT_3663 | Export or membrane protein. | Pyrimidine operon regulatory protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.929 |
| RMCT_3660 | upp | RMCT_3660 | RMCT_3437 | Export or membrane protein. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.483 |
| SurE | MazG | RMCT_1179 | RMCT_1525 | Survival protein SurE. | Nucleoside triphosphate pyrophosphohydrolase. | 0.910 |
| SurE | pyrF | RMCT_1179 | RMCT_3657 | Survival protein SurE. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.920 |
| SurE | pyrH | RMCT_1179 | RMCT_4235 | Survival protein SurE. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.927 |
| SurE | pyrR | RMCT_1179 | RMCT_3663 | Survival protein SurE. | Pyrimidine operon regulatory protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.916 |
| SurE | upp | RMCT_1179 | RMCT_3437 | Survival protein SurE. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.912 |
| carA | RMCT_3660 | RMCT_3659 | RMCT_3660 | Carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | Export or membrane protein. | 0.960 |
| carA | carB | RMCT_3659 | RMCT_3658 | Carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
| carA | pyrB | RMCT_3659 | RMCT_3662 | Carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
