STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AceE_2Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)    
Predicted Functional Partners:
Lpd
Dihydrolipoamide dehydrogenase.
  
 
 0.984
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
  
 0.969
Pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.940
PdhA
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
    
 0.934
CfiB
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.932
RMCT_0837
Oxidoreductase subunit alpha.
    
 0.922
AceE_1
Pyruvate dehydrogenase E1 component.
  
  
 
0.917
MaeB
Malate dehydrogenase.
    
 0.915
PdhB
Pyruvate dehydrogenase E1 component beta subunit pdhB.
    
 0.911
RMCT_0836
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.909
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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