dtd protein (Mycolicibacterium thermoresistibile)

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dtd

D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (148 aa)

Predicted Functional Partners:

RMCT_3843

0.627

GlnA_2

0.624

RMCT_4559

0.551

RelA_1

0.491

RelA_2

0.491

RMCT_3554

0.485

RMCT_3842

0.483

mnmA

0.446

RMCT_2027

0.443

RMCT_3846

0.441

Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GlnA_2	RMCT_3843	RMCT_3845	RMCT_3843	Glutamine synthetase glnA1.	DoxX family protein.	0.467
GlnA_2	RMCT_3846	RMCT_3845	RMCT_3846	Glutamine synthetase glnA1.	RDD domain-containing protein.	0.763
GlnA_2	RMCT_4559	RMCT_3845	RMCT_4559	Glutamine synthetase glnA1.	Stage II sporulation protein E.	0.495
GlnA_2	dtd	RMCT_3845	RMCT_3844	Glutamine synthetase glnA1.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.624
RMCT_2027	dtd	RMCT_2027	RMCT_3844	Uncharacterized protein, MTH1187 family.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.443
RMCT_3554	dtd	RMCT_3554	RMCT_3844	Amino acid-binding ACT domain-containing protein.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.485
RMCT_3842	RMCT_3843	RMCT_3842	RMCT_3843	acyl-CoA dehydrogenase.	DoxX family protein.	0.579
RMCT_3842	RMCT_4559	RMCT_3842	RMCT_4559	acyl-CoA dehydrogenase.	Stage II sporulation protein E.	0.523
RMCT_3842	dtd	RMCT_3842	RMCT_3844	acyl-CoA dehydrogenase.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.483
RMCT_3843	GlnA_2	RMCT_3843	RMCT_3845	DoxX family protein.	Glutamine synthetase glnA1.	0.467
RMCT_3843	RMCT_3842	RMCT_3843	RMCT_3842	DoxX family protein.	acyl-CoA dehydrogenase.	0.579
RMCT_3843	dtd	RMCT_3843	RMCT_3844	DoxX family protein.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.627
RMCT_3846	GlnA_2	RMCT_3846	RMCT_3845	RDD domain-containing protein.	Glutamine synthetase glnA1.	0.763
RMCT_3846	dtd	RMCT_3846	RMCT_3844	RDD domain-containing protein.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.441
RMCT_4559	GlnA_2	RMCT_4559	RMCT_3845	Stage II sporulation protein E.	Glutamine synthetase glnA1.	0.495
RMCT_4559	RMCT_3842	RMCT_4559	RMCT_3842	Stage II sporulation protein E.	acyl-CoA dehydrogenase.	0.523
RMCT_4559	RelA_1	RMCT_4559	RMCT_2967	Stage II sporulation protein E.	Metal dependent phosphohydrolase.	0.530
RMCT_4559	RelA_2	RMCT_4559	RMCT_3728	Stage II sporulation protein E.	GTP pyrophosphokinase relA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.530
RMCT_4559	dtd	RMCT_4559	RMCT_3844	Stage II sporulation protein E.	D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.	0.551
RelA_1	RMCT_4559	RMCT_2967	RMCT_4559	Metal dependent phosphohydrolase.	Stage II sporulation protein E.	0.530

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