Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RMCT_3942HAD superfamily hydrolase. (233 aa)    
Predicted Functional Partners:
RMCT_4221
Putative uncharacterized protein.
  
    0.787
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
  
  
 0.720
hisE
phosphoribosyl-ATP pyrophosphatase.
     
 0.716
XylE
MFS transporter, sugar porter family; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
     
 0.668
AzoB
dTDP-glucose-46-dehydratase.
  
    0.590
MerA
Mercuric reductase.
  
 
 0.580
TrmI
tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
      0.548
RMCT_4092
Amidohydrolase.
 
 
 0.530
PfkB_1
6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
    0.515
RMCT_3946
Integral membrane protein.
       0.492
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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