Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MerAMercuric reductase. (458 aa)    
Predicted Functional Partners:
Kgd
Alpha-ketoglutarate decarboxylase.
  
 0.990
AcoB
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit.
 
 0.982
RMCT_3946
Integral membrane protein.
 
     0.920
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.918
PdhB
Pyruvate dehydrogenase E1 component beta subunit pdhB.
 
 0.911
DlaT
Dihydrolipoamide acetyltransferase.
 0.897
PdhA
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
 
 
 0.847
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
 0.812
RMCT_1636
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component.
  
 0.812
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.763
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.