Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
VraRTwo-component system, regulatory protein. (393 aa)    
Predicted Functional Partners:
RMCT_4559
Stage II sporulation protein E.
  
 
 0.931
RMCT_4002
Ketosteroid isomerase-like protein.
 
    0.873
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
 0.866
NreB_1
GAF sensor signal transduction histidine kinase.
 
 
 0.838
AdrA
Diguanylate cyclase.
  
 
 0.789
NreB_2
Two-component system sensor kinase.
 
 
 0.771
NreC_2
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.765
RMCT_4221
Putative uncharacterized protein.
  
  
 0.760
DevS
GAF sensor signal transduction histidine kinase.
 
 
 0.733
NreC_3
Two-component system response regulator.
 
 
 0.684
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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