| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DnaK_4 | GlnR | RMCT_3799 | RMCT_4020 | Molecular chaperone-like protein. | Heat shock protein transcriptional repressor HspR. | 0.548 |
| DnaK_4 | Pks2 | RMCT_3799 | RMCT_4379 | Molecular chaperone-like protein. | Polyketide synthase pks5. | 0.558 |
| DnaK_4 | PpsA_2 | RMCT_3799 | RMCT_0416 | Molecular chaperone-like protein. | Beta-ketoacyl synthase. | 0.563 |
| DnaK_4 | clpB | RMCT_3799 | RMCT_4012 | Molecular chaperone-like protein. | Endopeptidase ATP binding protein subunit B clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.674 |
| DnaK_4 | dnaJ-2 | RMCT_3799 | RMCT_4021 | Molecular chaperone-like protein. | Chaperone dnaJ1; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.853 |
| DnaK_4 | groEL | RMCT_3799 | RMCT_0566 | Molecular chaperone-like protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.860 |
| DnaK_4 | groEL-2 | RMCT_3799 | RMCT_2684 | Molecular chaperone-like protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.855 |
| DnaK_4 | grpE | RMCT_3799 | RMCT_4022 | Molecular chaperone-like protein. | GrpE protein HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...] | 0.934 |
| GlnR | DnaK_4 | RMCT_4020 | RMCT_3799 | Heat shock protein transcriptional repressor HspR. | Molecular chaperone-like protein. | 0.548 |
| GlnR | clpB | RMCT_4020 | RMCT_4012 | Heat shock protein transcriptional repressor HspR. | Endopeptidase ATP binding protein subunit B clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.725 |
| GlnR | dnaJ-2 | RMCT_4020 | RMCT_4021 | Heat shock protein transcriptional repressor HspR. | Chaperone dnaJ1; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.987 |
| GlnR | dnaK | RMCT_4020 | RMCT_4023 | Heat shock protein transcriptional repressor HspR. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.982 |
| GlnR | groEL | RMCT_4020 | RMCT_0566 | Heat shock protein transcriptional repressor HspR. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.501 |
| GlnR | groEL-2 | RMCT_4020 | RMCT_2684 | Heat shock protein transcriptional repressor HspR. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.507 |
| GlnR | grpE | RMCT_4020 | RMCT_4022 | Heat shock protein transcriptional repressor HspR. | GrpE protein HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...] | 0.975 |
| Pks2 | DnaK_4 | RMCT_4379 | RMCT_3799 | Polyketide synthase pks5. | Molecular chaperone-like protein. | 0.558 |
| Pks2 | PpsA_2 | RMCT_4379 | RMCT_0416 | Polyketide synthase pks5. | Beta-ketoacyl synthase. | 0.998 |
| Pks2 | dnaJ-2 | RMCT_4379 | RMCT_4021 | Polyketide synthase pks5. | Chaperone dnaJ1; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.893 |
| Pks2 | dnaK | RMCT_4379 | RMCT_4023 | Polyketide synthase pks5. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.558 |
| Pks2 | groEL | RMCT_4379 | RMCT_0566 | Polyketide synthase pks5. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.566 |
