| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AcyP | RMCT_4148 | RMCT_3502 | RMCT_4148 | Acylphosphatase. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| AcyP | RMCT_4229 | RMCT_3502 | RMCT_4229 | Acylphosphatase. | Lactate 2-monooxygenase. | 0.904 |
| AcyP | ackA | RMCT_3502 | RMCT_2737 | Acylphosphatase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.917 |
| AcyP | acsA | RMCT_3502 | RMCT_0114 | Acylphosphatase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.905 |
| AdhC2 | BphJ | RMCT_3597 | RMCT_1944 | NADP-dependent alcohol dehydrogenase C. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.906 |
| AdhC2 | RMCT_4148 | RMCT_3597 | RMCT_4148 | NADP-dependent alcohol dehydrogenase C. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.935 |
| AdhC2 | ackA | RMCT_3597 | RMCT_2737 | NADP-dependent alcohol dehydrogenase C. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.498 |
| BphJ | AdhC2 | RMCT_1944 | RMCT_3597 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | NADP-dependent alcohol dehydrogenase C. | 0.906 |
| BphJ | MmsA | RMCT_1944 | RMCT_0519 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Methylmalonate-semialdehyde dehydrogenase. | 0.821 |
| BphJ | RMCT_4148 | RMCT_1944 | RMCT_4148 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| BphJ | acsA | RMCT_1944 | RMCT_0114 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.909 |
| GadA | GdhA | RMCT_0558 | RMCT_1548 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.915 |
| GadA | RMCT_4148 | RMCT_0558 | RMCT_4148 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.928 |
| GadA | panD | RMCT_0558 | RMCT_3318 | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.906 |
| GdhA | GadA | RMCT_1548 | RMCT_0558 | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate decarboxylase gadB; Belongs to the group II decarboxylase family. | 0.915 |
| GdhA | MmsA | RMCT_1548 | RMCT_0519 | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Methylmalonate-semialdehyde dehydrogenase. | 0.649 |
| GdhA | RMCT_4148 | RMCT_1548 | RMCT_4148 | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.926 |
| GdhA | acsA | RMCT_1548 | RMCT_0114 | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.568 |
| MmsA | BphJ | RMCT_0519 | RMCT_1944 | Methylmalonate-semialdehyde dehydrogenase. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.821 |
| MmsA | GdhA | RMCT_0519 | RMCT_1548 | Methylmalonate-semialdehyde dehydrogenase. | Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.649 |