Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ArlS_1Signal transduction histidine kinase. (492 aa)    
Predicted Functional Partners:
CopR
Two-component system response regulator.
 
 
 0.977
RMCT_4559
Stage II sporulation protein E.
  
 
 0.899
MprA
Two component response transcriptional regulatory protein MprA.
 
 
 0.855
MtrA
Two component system sensor transduction transcriptional regulatory protein mtrA.
 
 
 0.851
PrrA
Two component transcriptional regulator.
 
 
 0.841
RegX3
Two component system sensor transduction protein regX3.
 
 
 0.830
TcrA
Two-component system response regulator.
 
 
 0.797
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
 0.658
RMCT_4153
Uncharacterized protein.
       0.628
WalR
Transcriptional regulator.
 
 
 0.586
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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