Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RMCT_4207Amidohydrolase. (349 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.783
NfdA_2
Amidohydrolase.
 
     0.565
glnD
PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
       0.549
GlnB
Nitrogen regulatory protein P-II glnB; Belongs to the P(II) protein family.
       0.515
Gbh
Agmatinase; Belongs to the arginase family.
  
  
 0.503
RMCT_3037
Response regulator.
  
     0.478
YngG_2
hydroxymethylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
    0.460
RMCT_3850
TIGR01777 family protein.
  
    0.445
RMCT_3922
NAD-dependent nucleoside-diphosphate sugar epimerase.
  
    0.445
PatB
Aminotransferase.
  
    0.442
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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