Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HpcHHpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (268 aa)    
Predicted Functional Partners:
GabD_1
NAD-dependent aldehyde dehydrogenase.
  
 
 0.921
GabD_2
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.921
IdnD
Theronine dehydrogenase-like Zn-dependent dehydrogenase.
 
     0.859
MhpD
2-keto-4-pentenoate hydratase.
  
 0.805
RMCT_4249
Cytochrome P450 130.
       0.798
RMCT_4250
Cytochrome P450.
       0.798
CpnA_1
Short-chain dehydrogenase/reductase SDR.
     
 0.746
RMCT_4248
Gluconolactonase.
 
   
 0.721
Lip2_7
Alpha/beta hydrolase domain-containing protein.
       0.706
HapE_6
Cyclohexanone monooxygenase.
       0.685
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (16%) [HD]