RMCT_4327 protein (Mycolicibacterium thermoresistibile)

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RMCT_4327

3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (241 aa)

Predicted Functional Partners:

ResA_2

0.836

ahpD

0.836

ResA_1

0.836

RMCT_3822

0.830

PcrA_3

0.790

RMCT_4328

0.785

TrxB

0.758

AhpF

0.740

SodC_1

0.689

sodB

0.659

Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AhpF	RMCT_4327	RMCT_3831	RMCT_4327	Thioredoxin reductase.	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.740
AhpF	ResA_1	RMCT_3831	RMCT_2600	Thioredoxin reductase.	Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.	0.577
AhpF	ResA_2	RMCT_3831	RMCT_0107	Thioredoxin reductase.	Thiol-disulfide isomerase-like thioredoxin.	0.577
PcrA_3	RMCT_4327	RMCT_2357	RMCT_4327	ATP-dependent DNA helicase II uvrD2.	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.790
PcrA_3	TrxB	RMCT_2357	RMCT_1126	ATP-dependent DNA helicase II uvrD2.	Thioredoxin reductase.	0.450
RMCT_3822	RMCT_4327	RMCT_3822	RMCT_4327	Peroxiredoxin ahpE.	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.830
RMCT_3822	ahpD	RMCT_3822	RMCT_2078	Peroxiredoxin ahpE.	Alkyl hydroperoxide reductase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.	0.571
RMCT_4327	AhpF	RMCT_4327	RMCT_3831	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Thioredoxin reductase.	0.740
RMCT_4327	PcrA_3	RMCT_4327	RMCT_2357	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	ATP-dependent DNA helicase II uvrD2.	0.790
RMCT_4327	RMCT_3822	RMCT_4327	RMCT_3822	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Peroxiredoxin ahpE.	0.830
RMCT_4327	RMCT_4328	RMCT_4327	RMCT_4328	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Putative uncharacterized protein.	0.785
RMCT_4327	ResA_1	RMCT_4327	RMCT_2600	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.	0.836
RMCT_4327	ResA_2	RMCT_4327	RMCT_0107	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Thiol-disulfide isomerase-like thioredoxin.	0.836
RMCT_4327	SodC_1	RMCT_4327	RMCT_2704	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Periplasmic superoxide dismutase [Cu-Zn] sodC; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.689
RMCT_4327	TrxB	RMCT_4327	RMCT_1126	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Thioredoxin reductase.	0.758
RMCT_4327	ahpD	RMCT_4327	RMCT_2078	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Alkyl hydroperoxide reductase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.	0.836
RMCT_4327	sodB	RMCT_4327	RMCT_3486	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Superoxide dismutase Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.659
RMCT_4328	RMCT_4327	RMCT_4328	RMCT_4327	Putative uncharacterized protein.	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.785
ResA_1	AhpF	RMCT_2600	RMCT_3831	Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.	Thioredoxin reductase.	0.577
ResA_1	RMCT_4327	RMCT_2600	RMCT_4327	Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.	3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.836

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