STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CobI_1Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. (499 aa)    
Predicted Functional Partners:
CobM
Precorrin-4 c11-methyltransferase cobM; Belongs to the precorrin methyltransferase family.
 
 0.999
CobH
precorrin-8X methylmutase.
  
 0.999
CobL
Precorrin-6y methyltransferase cobL.
 
  
 0.998
RMCT_4354
Cobalamin biosynthesis protein cobG.
 
 
 0.997
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.995
CysG_2
Multi-functional enzyme siroheme synthase cysG: uroporphyrin-III C-methyltransferase + precorrin-2 oxidase + ferrochelatase.
 
 0.995
CobK
Cobalt-precorrin-6x reductase.
 
  
 0.992
CysG_1
uroporphyrin-III C-methyltransferase hemD.
  
 
 0.988
cobS
Cobalamin 5-phosphate synthase cobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.969
RMCT_3587
SAM-dependent methyltransferase.
  
  
 0.938
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.