| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CobH | CobI_1 | RMCT_4353 | RMCT_4352 | precorrin-8X methylmutase. | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | 0.999 |
| CobH | CobI_2 | RMCT_4353 | RMCT_1689 | precorrin-8X methylmutase. | precorrin-6A synthase deacetylating. | 0.913 |
| CobH | CobK | RMCT_4353 | RMCT_4349 | precorrin-8X methylmutase. | Cobalt-precorrin-6x reductase. | 0.974 |
| CobH | CobL | RMCT_4353 | RMCT_4347 | precorrin-8X methylmutase. | Precorrin-6y methyltransferase cobL. | 0.999 |
| CobH | CobM | RMCT_4353 | RMCT_4348 | precorrin-8X methylmutase. | Precorrin-4 c11-methyltransferase cobM; Belongs to the precorrin methyltransferase family. | 0.980 |
| CobH | CobN | RMCT_4353 | RMCT_4355 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein cobN. | 0.890 |
| CobH | RMCT_4354 | RMCT_4353 | RMCT_4354 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein cobG. | 0.994 |
| CobH | cobB-3 | RMCT_4353 | RMCT_4280 | precorrin-8X methylmutase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.997 |
| CobH | cobD | RMCT_4353 | RMCT_3824 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.894 |
| CobH | cobQ | RMCT_4353 | RMCT_4268 | precorrin-8X methylmutase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.978 |
| CobI_1 | CobH | RMCT_4352 | RMCT_4353 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | precorrin-8X methylmutase. | 0.999 |
| CobI_1 | CobI_2 | RMCT_4352 | RMCT_1689 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | precorrin-6A synthase deacetylating. | 0.809 |
| CobI_1 | CobK | RMCT_4352 | RMCT_4349 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobalt-precorrin-6x reductase. | 0.992 |
| CobI_1 | CobL | RMCT_4352 | RMCT_4347 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Precorrin-6y methyltransferase cobL. | 0.998 |
| CobI_1 | CobM | RMCT_4352 | RMCT_4348 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Precorrin-4 c11-methyltransferase cobM; Belongs to the precorrin methyltransferase family. | 0.999 |
| CobI_1 | CobN | RMCT_4352 | RMCT_4355 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein cobN. | 0.929 |
| CobI_1 | RMCT_4354 | RMCT_4352 | RMCT_4354 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein cobG. | 0.997 |
| CobI_1 | cobB-3 | RMCT_4352 | RMCT_4280 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.938 |
| CobI_1 | cobD | RMCT_4352 | RMCT_3824 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.872 |
| CobI_1 | cobQ | RMCT_4352 | RMCT_4268 | Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |