STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCT_4354Cobalamin biosynthesis protein cobG. (378 aa)    
Predicted Functional Partners:
CobI_1
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Bifunctional protein, cobI-cobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase; Belongs to the precorrin methyltransferase family.
 
 
 0.997
CobH
precorrin-8X methylmutase.
  
 0.994
cysC
Bifunctional sulfate adenyltransferase/adenylylsulfate kinase cysN/cysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.961
NarB
Sulfite reductase (NADPH) subunit alpha.
  
 
 0.913
CysG_2
Multi-functional enzyme siroheme synthase cysG: uroporphyrin-III C-methyltransferase + precorrin-2 oxidase + ferrochelatase.
  
  
 0.889
CobL
Precorrin-6y methyltransferase cobL.
 
   
 0.830
CobN
Cobalamin biosynthesis protein cobN.
 
   
 0.793
CobK
Cobalt-precorrin-6x reductase.
 
   
 0.787
CysW_2
Sulfate-transport integral membrane protein ABC transporter cysW.
  
  
 0.741
CysA_2
Molybdenum-transport ATP-binding protein ABC transporter modC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
  
  
 0.708
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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