Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Cya_1Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (438 aa)    
Predicted Functional Partners:
RMCT_4559
Stage II sporulation protein E.
  
 
 0.979
RMCT_1972
Adenylyl cyclase.
 
 0.976
Gmr
GAF sensor-containing diguanylate cyclase/phosphodiesterase.
 
 
 0.968
CyaB_3
Transmembrane protein.
 
0.951
CyaB_1
Adenylate cyclase, family protein 3.
 
0.951
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.911
RelA_2
GTP pyrophosphokinase relA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.911
MazG
Nucleoside triphosphate pyrophosphohydrolase.
    
 0.910
AdrA
Diguanylate cyclase.
  
 
 0.903
YnaI
Small-conductance mechanosensitive channel.
 
 0.891
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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