Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PdtaRTwo component system transcriptional regulator. (206 aa)    
Predicted Functional Partners:
PdtaS
Two component sensor kinase.
 
   
 0.885
BraC
Extracellular ligand-binding receptor.
  
 
 0.780
RpsA
30S ribosomal protein S1.
 
    0.759
GltB
Ferredoxin-dependent glutamate synthase, large subunit gltB.
  
  
 0.606
RMCT_3821
Protein of unknown function.
   
    0.562
atpD
F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
  
 0.561
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
     
 0.527
RMCT_4455
Branched chain amino acid transport permease; Belongs to the binding-protein-dependent transport system permease family.
     
 0.509
LivH_1
Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
     
 0.508
RMCT_2150
Amino acid/amide ABC transporter substrate-binding protein, HAAT family.
  
 
 0.501
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (14%) [HD]