STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RMCT_4472Putative uncharacterized protein. (338 aa)    
Predicted Functional Partners:
RdgB
Nucleoside triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.770
nhaA
Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
    0.760
TesB_3
acyl-CoA thioesterase.
       0.545
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
  
 0.477
SigM
Sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.477
SigE
ECF subfamily RNA polymerase sigma-24 subunit; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.477
RMCT_0634
RNA polymerase sigma factor SigJ; Belongs to the sigma-70 factor family.
  
  
 0.477
RpoE_4
RNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.477
CnrH
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.477
whiB-3
WhiB family regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
  
 0.477
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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