Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MenE_3AMP-dependent synthetase and ligase. (499 aa)    
Predicted Functional Partners:
Pks2
Polyketide synthase pks5.
  
 0.908
RMCT_4644
Putative uncharacterized protein.
 
     0.908
PpsA_2
Beta-ketoacyl synthase.
  
 0.808
EryA_1
Acyl transferase domain-containing protein.
  
 0.805
RMCT_2488
Putative uncharacterized protein.
 
     0.729
RMCT_0850
Putative uncharacterized protein.
 
     0.728
RMCT_2208
Putative uncharacterized protein.
 
     0.728
PpsA_7
Polyketide synthase pks13.
  
 0.717
FadK_12
cyclohex-1-ene-1-carboxylate:CoA ligase.
 
    
0.673
EryA_2
Polyketide synthetase mbtC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.671
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (12%) [HD]