STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGD64031.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)    
Predicted Functional Partners:
A2160_04540
Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
OGD62501.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.672
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
  0.536
OGD64032.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.409
OGD64028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.408
OGD64029.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.408
Your Current Organism:
Beckwithbacteria bacterium RBG13429
NCBI taxonomy Id: 1797457
Other names: C. Beckwithbacteria bacterium RBG_13_42_9, Candidatus Beckwithbacteria bacterium RBG_13_42_9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.