STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGY44808.1Hypothetical protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (140 aa)    
Predicted Functional Partners:
OGY45271.1
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.980
OGY45101.1
Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.977
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 0.919
OGY44810.1
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.871
thyA-2
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 0.854
A2729_05030
Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.836
OGY44803.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.832
OGY45283.1
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.826
OGY43943.1
Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.824
OGY44327.1
Nucleoside-diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.823
Your Current Organism:
Buchananbacteria bacterium RIFCSPHIGHO201FULL3914
NCBI taxonomy Id: 1797532
Other names: C. Buchananbacteria bacterium RIFCSPHIGHO2_01_FULL_39_14, Candidatus Buchananbacteria bacterium RIFCSPHIGHO2_01_FULL_39_14
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