STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSHypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1143 aa)    
Predicted Functional Partners:
argS
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.999
OGY58963.1
methionine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
leuS
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
0.989
lysS
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.946
A3F24_01165
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD; Too many ambiguous residues; incomplete; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
0.884
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.867
A3F24_01070
Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.
   
 0.862
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.862
OGY60031.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.851
Your Current Organism:
Colwellbacteria bacterium RIFCSPHIGHO212FULL4417
NCBI taxonomy Id: 1797689
Other names: C. Colwellbacteria bacterium RIFCSPHIGHO2_12_FULL_44_17, Candidatus Colwellbacteria bacterium RIFCSPHIGHO2_12_FULL_44_17
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