STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGY59534.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)    
Predicted Functional Partners:
OGY59533.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
OGY59380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the folylpolyglutamate synthase family.
  
 
 0.878
OGY59336.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.774
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
 
 0.724
OGY59531.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.718
OGY59532.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.718
OGY59680.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.670
OGY59111.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.579
OGY59535.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.572
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.550
Your Current Organism:
Colwellbacteria bacterium RIFCSPLOWO201FULL4810
NCBI taxonomy Id: 1797690
Other names: C. Colwellbacteria bacterium RIFCSPLOWO2_01_FULL_48_10, Candidatus Colwellbacteria bacterium RIFCSPLOWO2_01_FULL_48_10
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